全文获取类型
收费全文 | 26794篇 |
免费 | 4669篇 |
国内免费 | 3739篇 |
专业分类
化学 | 19645篇 |
晶体学 | 401篇 |
力学 | 1821篇 |
综合类 | 283篇 |
数学 | 3066篇 |
物理学 | 9986篇 |
出版年
2024年 | 24篇 |
2023年 | 485篇 |
2022年 | 576篇 |
2021年 | 800篇 |
2020年 | 1034篇 |
2019年 | 1047篇 |
2018年 | 868篇 |
2017年 | 903篇 |
2016年 | 1247篇 |
2015年 | 1277篇 |
2014年 | 1580篇 |
2013年 | 1963篇 |
2012年 | 2572篇 |
2011年 | 2662篇 |
2010年 | 1859篇 |
2009年 | 1748篇 |
2008年 | 1883篇 |
2007年 | 1709篇 |
2006年 | 1679篇 |
2005年 | 1390篇 |
2004年 | 1027篇 |
2003年 | 824篇 |
2002年 | 802篇 |
2001年 | 717篇 |
2000年 | 532篇 |
1999年 | 504篇 |
1998年 | 435篇 |
1997年 | 379篇 |
1996年 | 371篇 |
1995年 | 309篇 |
1994年 | 264篇 |
1993年 | 215篇 |
1992年 | 220篇 |
1991年 | 219篇 |
1990年 | 158篇 |
1989年 | 135篇 |
1988年 | 93篇 |
1987年 | 74篇 |
1986年 | 88篇 |
1985年 | 71篇 |
1984年 | 61篇 |
1983年 | 48篇 |
1982年 | 35篇 |
1981年 | 35篇 |
1980年 | 32篇 |
1979年 | 22篇 |
1978年 | 24篇 |
1977年 | 25篇 |
1976年 | 23篇 |
1973年 | 26篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
21.
本文采用分子动力学方法研究了FeCoCrCuNi高熵合金裂纹及孔洞模型结构在不同轴向拉伸应变速率下的力学与微观结构演化机理. 结果表明:应变速率越高FeCoCrCuNi裂纹结构对应更高的过冲应变和过冲应力,其主要原因是高拉伸速率会导致高强度的BCC结构及孪晶结构的生成,而BCC结构及孪晶结构的产生进而会抑制应力的下降,通过应力-应变曲线,可知FeCoCrCuNi裂纹模型在轴向应力作用下表现为塑性形变. 对于不同尺寸的孔洞FeCoCrCuNi裂纹模型的应力模拟与结构分析,可以得出:孔洞尺寸越大, FeCoCrCuNi裂纹结构对应的过冲应变和过冲应力越小,其主要原因是大尺寸的孔洞造成孔洞之间产生裂纹的,进而会影响这个材料的屈服应变和屈服强度. 相似文献
22.
Structural Chemistry - The density functional theory (DFT) was applied to investigate the structure, optical properties, and non-bonded interactions of the cyclo-pentazolate salt... 相似文献
23.
Xu Liu Ruoyu Liu Jiaxing Qiu Prof. Dr. Xu Cheng Prof. Dr. Guigen Li 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(33):14066-14071
We report a method for the electrochemical deuteration of α,β-unsaturated carbonyl compounds under catalyst- and external-reductant-free conditions, with deuteration rates as high as 99 % and yields up to 91 % in 2 h. The use of graphite felt for both the cathode and the anode was key to ensuring chemoselectivity and high deuterium incorporation under neutral conditions without the need for an external reductant. This method has a number of advantages over previously reported deuteration reactions that use stoichiometric metallic reductants. Mechanistic experiments showed that O2 evolution at the anode not only eliminates the need for an external reductant but also regulates the pH of the reaction mixture, keeping it approximately neutral. 相似文献
24.
Tongtong Feng Dr. Yingxiang Ye Xiao Liu Hui Cui Dr. Zhiqiang Li Dr. Ying Zhang Dr. Bin Liang Prof. Huanrong Li Prof. Banglin Chen 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(48):21936-21941
Temperature sensors play a significant role in biology, chemistry, and engineering, especially those that can work accurately in a noninvasive manner. We adopted a photoinduced post-synthetic copolymerization strategy to realize a membranous ratiometric luminescent thermometer based on the emissions of two lanthanide ions. This novel mixed-lanthanide polyMOF membrane exhibits not only the integrity and temperature sensing behaviour of the Ln-MOF powder but also excellent mechanical properties, such as flexibility, elasticity, and processability. Moreover, the polyMOF membrane shows remarkable stability under harsh conditions, including high humidity, strong acid and alkali (pH 0–14), which allowed the mapping of temperature distributions in extreme circumstances. This work highlights a simple strategy for polyMOF membrane formation and pushes forward the further practical application of Ln-MOF-based luminescent thermometers in various fields and conditions. 相似文献
25.
26.
27.
Adlerberth Josefin Meng Qinglai Mecklenburg Michael Tian Zengmin Zhou Yikai Bülow Leif Xie Bin 《Journal of Thermal Analysis and Calorimetry》2020,140(2):763-771
Journal of Thermal Analysis and Calorimetry - Real-time monitoring of patient’s blood metabolites, such as glucose and lactate, could potentially improve surgery and recovery outcomes for... 相似文献
28.
The etch-stop structure including the in-situ SiN and AlGaN/GaN barrier is proposed for high frequency applications.The etch-stop process is realized by placing an in-situ SiN layer on the top of the thin AlGaN barrier.F-based etching can be self-terminated after removing SiN,leaving the AlGaN barrier in the gate region.With this in-situ SiN and thin barrier etch-stop structure,the short channel effect can be suppressed,meanwhile achieving highly precisely controlled and low damage etching process.The device shows a maximum drain current of 1022 mA/mm,a peak transconductance of 459 mS/mm,and a maximum oscillation frequency(fmax)of 248 GHz. 相似文献
29.
Meining Li Huahua Li Hong Yang Rina Cheng Pengdou Zheng Rui Guo 《Biomedical chromatography : BMC》2020,34(4):e4799
Spermiogenesis in mammals is an exclusive process during which haploid round spermatids mature into spermatozoa in the testis. Any abnormality in the process of spermiogenesis may result in male infertility. The aim of the present study was to characterize the differentially expressed proteins between round and elongated spermatids in mice using label-free quantitative mass spectrometry. Of the 2411 proteins identified in this study, 333 were differentially expressed with a ≥10-fold change, including 208 upregulated proteins and 125 downregulated proteins in round spermatids relative to elongated spermatids. Gene Ontology analysis showed that these differentially expressed proteins were categorized into 10 types of subcellular localizations, 9 molecular functions, and were involved in 9 biological processes. All the identified proteins participated in 268 different pathways. In addition, ubiquitin-mediated proteolysis and the proteasome pathway, autophagy, lysosome, and apoptosis pathways were involved in the mechanism of spermiogenesis. Our data may provide valuable information for a better understanding of spermiogenesis and help improve the diagnosis and treatment of male factor infertility. 相似文献
30.
Yangang Cheng Yan Liu Jinyan Tan Yanping Sun Wei Guan Yuan Liu Bingyou Yang Haixue Kuang 《Biomedical chromatography : BMC》2020,34(9):e4881
Our previous work demonstrated that total withanolides of Datura metel L. leaves (TWD) exhibited excellent therapeutic effects on psoriasis. However, current knowledge of its mechanisms is incomplete. In this study, integrated spleen and thymus untargeted metabolomics were used to analyze the changes in endogenous metabolites underlying the immunosuppressive activity of TWD on psoriasis animal models induced by imiquimod. The results suggested that TWD treatment markedly attenuated imiquimod-induced psoriasis and showed significant immunosuppressive activity as evidenced by decreased elevation index of spleen and thymus. Meanwhile, TWD significantly reversed the elevation of immunoregulatory factors, including IL-10, IL-17, IL-22 and IL-23. Multivariate trajectory analysis revealed that TWD treatment could restore the psoriasis-disturbed spleen and thymus metabolite profiles towards the normal metabolic status. A total of 25 and 27 metabolites associated with the immunomodulatory effects for which levels changed markedly upon treatment have been identified in spleen and thymus, respectively. These differential metabolites were mainly involved in amino acid metabolism, nucleotide metabolism, fatty acid metabolism and lipid metabolism. Our investigation provided a holistic view of TWD for intervention in psoriasis through immunoregulation and provided further scientific information in vivo about a clinical value of TWD for psoriasis. 相似文献